Businesses For Sale in Charleston County, SC

Charleston, SC

This growing outdoor construction company delivers residential and commercial fencing projects with the operational efficiency, supplier strength, and quality control that set it apart from the...

$259,000

Charleston, SC

Families often need reliable help so older adults can remain at home while receiving assistance with daily routines. This company coordinates non-medical in-home services such as companionship,...

$173,900

Charleston, SC

For Sale this home-based landscaping company In Charleston. The sale price includes a leased and wrapped work vehicle and advanced technology application. This company supports our client’s lawncare...

$160,000

Mount Pleasant, SC

For Sale: Established Wine Bar in Mount Pleasant, SC Location: Mount Pleasant, South Carolina Size: 1,465 SF Asking Price: $159,000 Confidential Listing Overview This is an opportunity to acquire a...

$159,000

Charleston, SC

This is a rare opportunity to acquire a finely tuned outdoor services operation built on modern technology and diversified service offerings. Unlike traditional lawn care businesses, this operation is...

$429,999

Charleston, SC

This “non-Medical” senior care company is for sale. This has been a well-performing business. This unit is part of a national brand that was one of the very first companies in the United States to...

$262,499

North Charleston, SC

Turn-key restaurant and bar in highly sought-after Park Circle market. This turnkey space occupies roughly 2,100 square feet of prime commercial space with below-market lease terms available....

$263,000

Charleston, SC

This operation specializes in renovating outdoor spaces through synthetic ground cover installation and periodic care for residential and commercial clients. Expanding water conservation policies...

$299,999

Charleston, SC

Established Japanese hibachi steakhouse and sushi bar in the Charleston, South Carolina metro, offered together with the freestanding building and land it occupies. More than a decade of continuous...

$2,395,000

Available Nationwide

Ranked as a top Organization/Storage Systems franchise by 2026 Entrepreneur Franchise 500®. 53% of appointments resulted in a closed order!*

$50,000

Charleston, SC

A profitable, long-established home management company serving luxury second-home owners in one of coastal South Carolina's most desirable private communities, roughly half an hour from Charleston....

Not Disclosed

Charleston, SC

Established Charleston gift and artisan gallery in a prime downtown location, offering a distinctive mix of handcrafted jewelry, pottery, glass, artwork, home décor, and gifts from a broad network of...

$295,000

Charleston, SC

This insulation business operates in a functional, energy-efficiency-driven category serving homeowners, builders, and commercial property owners. Properly installed insulation helps limit heat...

$464,999

Charleston, SC

Lucrative and with plenty of room to grow, Dryer Vent Cleaning business covering Charleston SC and surroundings. Low overhead & great - great margins. The new owner, or someone the new owner trusts,...

$100,000

Charleston County, SC

Profitable Liquor Store. This Liquor Store is located on one of the busiest roads in the Charleston Area, in a large (mature) shopping complex surrounded by National Brands. The Store is 1200 Square...

$377,000

Charleston County, SC

LISTING ID # 36194 Drop-Ship Shopify E-Commerce Business for Sale Laboratory Equipment & Scientific Supplies | Thousands of SKUs | 2025 Price Reduced! Motivated seller! Sales: $400,354 Overview For...

$49,000

Charleston County, SC

Highly sought after turn-key FedEx opportunity! High Value Territory! - 16 P&D Routes - Solid operation with experienced managers in place who can run a majority of the day to day operation. - Newer...

$1,100,000

North Charleston, SC

Stop scrolling if you’re looking for a real blue-collar, service-based business with staying power. This is a 12-year-old specialty battery sales, service, and recycling company in the Charleston,...

$245,000

Charleston County, SC

This coastal South Carolina opportunity allows an established agency or agent to acquire a decades-old book of business supported by a dual-office presence and an experienced, licensed team. The firm...

$300,000

Available in South Carolina

WSI is a digital marketing company with a strong international presence. Our Digital Marketing Consultants use their knowledge and expertise to make a difference for businesses all around the world.

$80,000

Charleston, SC

This property maintenance services business serves commercial, industrial, institutional, and residential clients. The sale includes a professionally wrapped, fully equipped service vehicle, along...

$197,900

Charleston, SC

The sale price includes a late model truck plus equipment, technology and inventory. The business is home based. This is a local contractor services business with high net profitability. 48% new...

$395,000

Charleston, SC

This established precision machining business combines modern CNC manufacturing with sophisticated digital infrastructure to create a highly scalable and defensible operation. The company operates...

$2,000,000

Chas, SC

This well-established full-service restaurant represents a compelling acquisition opportunity in Charleston's thriving dining market. Operating continuously for 34 years, the business has demonstrated...

$850,000

Charleston County, SC

Save thousands versus current lease rates! Established ice cream shop positioned on the highly coveted corner of Spring and King Street in Charleston County, offering exceptional visibility and foot...

$230,000

Charleston, SC

This business puts you at the forefront of the heating and cooling industry, one of the most dependable service markets available. It delivers installation, maintenance, and repair services for both...

$489,000

Charleston, SC

Included with sale price all equipment, smallware’s, furniture package and inventories. 32.49% bottom line EBITDA in 2025. Excellent earnings largely because the business needs only 15% - 18% total...

$315,000

Charleston County, SC

An established, fully-operating specialty family care clinic running under a recognized national franchise brand in the greater Charleston, South Carolina market. Offered turnkey: all equipment, the...

$95,000

Charleston, SC

If you’ve ever dreamed of stepping into Charleston’s vibrant food scene — connecting with locals, visitors, and fellow food lovers every day — this is your opportunity. This turnkey mobile food...

$160,000

Available Nationwide

Unleash your entrepreneurial spirit with Grasons Estate Sales & Business Liquidations, the #1 home-based estate sales & business liquidations franchise! Tap into a proven and trusted brand that has redefined excellence in this market.

$50,000

Charleston, SC

This dynamic event rental business delivers a full range of inflatable attractions and party essentials across Massachusetts and Rhode Island. Renowned for attentive customer care and on-time service,...

$295,000

Chas, SC

This established restaurant operation represents a prime hospitality investment opportunity in downtown Charleston's central business district. The venue has maintained continuous operations with...

$750,000

Charleston, SC

Size: Approximately 2,390+ sq ft of building+ Outdoor patio. 1st Floor Retail space and 2 Income producing Airbnb rentals on the 2nd & 3rd Floor. Location: Prime location on busy Market Street in the...

$2,675,000

Charleston, SC

Confidential Listing - Premier Restaurant/bar Opportunity in Folly Beach, SC Asking Price:$665,000 Location:Folly Beach, South Carolina Overview: A rare opportunity to acquire a well-established...

$665,000

Available Nationwide

Ranked as a top Residential Cleaning franchise by 2026 Entrepreneur Franchise 500®. 91% recurring customers!*

$60,000

Charleston County, SC

This turnkey childcare center presents an exceptional opportunity for an experienced operator or investor to acquire a well-maintained, purpose-built facility in a stable, family-oriented community....

$895,000

Charleston County, SC

Long-established specialty baby and children’s retailer serving Charleston-area families since 2003. The business combines a trusted Mount Pleasant showroom for quality nursery furniture,...

$650,000

Charleston, SC

Step into ownership of an established Franchise for Sale with existing brand recognition, operating infrastructure, and a clear path for both immediate improvement and long term growth. This offering...

$250,000

Charleston, SC

This sounds like a boutique Pilates reformer studio. The clues point to a premium, community-driven fitness concept with a compact footprint, recurring membership revenue, and strong unit-level...

$625,000

Charleston County, SC

Established painting, restoration, and renovation contractor serving the greater Charleston and Lowcountry market. Founded in 2003, the business has built more than 20 years of goodwill through...

$1,590,000

Charleston Afb, SC

Operating in the HVAC services sector means working within a category where service is often required without delay, maintenance follows a regular schedule, and clients tend to remain with providers...

$316,108

Charleston, SC

Step into one of the Southeast's hottest hospitality markets. This established event décor and balloon installation business serves greater Charleston, SC — a premier wedding and special-event...

$99,000

Charleston, SC

Positioned just off King Street in one of Charleston's most walkable and sought after corridors, this beautifully built out Cafe for Sale ofers a rare opportunity to step directly into a thoughtfully...

$100,000

Charleston, SC

This specialty dryer vent cleaning business is for sale. Dryer fires happen every day and the most common reason is the dust and lint that builds up in your dryer’s vent. On average there are over...

$99,850

Available in South Carolina

High-profit B2B waste services franchise with patented tech, recurring revenue, and proven multi-unit success.

$100,000

Charleston County, SC

Oral Surgery Practice Low Country, SC Listing ID 1456858 $1,085,000 Description Fantastic opportunity to purchase a well established Low Country Oral Surgery office in South Carolina. Located in a...

$1,085,000

Charleston, SC

Businesses of every size need professional print and marketing materials on a consistent and ongoing basis, and this commercial printing and marketing services company has built its entire model...

$315,000

Charleston County, SC

This family-operated business has built a strong reputation for quality workmanship, reliability, and customer service, resulting in a loyal customer base and steady year-round demand. Key Services &...

$500,000

Charleston Afb, SC

Confidential Listing Summary Asking Price: $199,999 Base Rent: $2,200/month (increases to $2,500/month in Year 2) Location: Park Circle area, North Charleston, SC Lease Terms: 5-year lease starting...

$199,999

Johns Island, SC

Established health-focused cafe positioned in a high-traffic anchored retail center, serving the greater Charleston market. This turnkey operation specializes in premium smoothies, fresh salads, and...

$150,000

Awendaw, SC

Iconic Seewee Restaurant with a long history serving outstanding seafood and Lowcountry fare. Established full-service restaurant specializing in Lowcountry seafood and traditional Southern fare,...

$2,495,000

Charleston, SC

The sale price for this home-based business includes a wrapped and fully equipped truck, inventory, and equipment assets. Our focus is on the senior community, but we also service real estate...

$119,900

Charleston County, SC

Established premium coastal landscaping platform serving Charleston’s most desirable residential submarkets. The business provides a balanced mix of recurring maintenance contracts and higher-margin...

$1,000,000

Charleston, SC

Profitable and well-established liquor store available in a high-traffic, highly visible location. This turnkey business offers a wide selection of Liquor, wines, spirits, and specialty beverages,...

$300,000

Available in South Carolina

Recession-resistant contents restoration franchise—insurance-driven leads, high-ticket jobs, and scalable growth.

$100,000